Decided to maintain Annabelle from wreaking extra havoc, demonologists Ed and Lorraine Warren deliver the possessed doll to the locked artifacts room of their dwelling, putting her “safely” behind sacred glass and enlisting a priest’s holy blessing. However an unholy evening of horror awaits as Annabelle awakens the evil spirits within the room, who all set their sights on a brand new goal—the Warrens' ten-year-old daughter, Judy, and her buddies.