Soulless unfolds within the fictional city of Bell's Finish, a spot with a curse hanging over it since its 1700 founding. After a younger lady is killed in a automobile accident, her physique goes lacking en path to the hospital. Days later she is found behind an area resort, alive. In the meantime, phrase of her reanimation will get again to the DOD, the place a long time earlier, a failed covert analysis undertaking on tissue regeneration was carried out on the girl's mom. The DOD launches a relentless effort to seize her as she rapidly learns that attempting to return to the land of the dwelling threatens to destroy the folks she loves most.